gdc
Breast CancerFDA Approvals, News & UpdatesNewsworthy

Verzenio a New Targeted Therapy Approved for Metastatic Breast Cancer

Read about Verzenio, which was approved by the FDA in 2017, in combination with fulvestrant, for treatment of women with HR-positive, HER2-positive, HER2-negative advanced, or metastatic breast cancer that progressed after endocrine therapy.
December 2017 Vol 3 No 6

On September 28, 2017, the FDA approved Verzenio (abemaciclib; from Eli Lilly), a CDK4/CDK6 inhibitor, in combination with fulvestrant, for the treatment of women with HR-positive, HER2-negative advanced or metastatic breast cancer that progressed after endocrine therapy, as well as for use alone in patients whose metastatic breast cancer progressed after endocrine therapy and after previous use of chemotherapy in the metastatic setting.

“Verzenio provides a new targeted treatment option for certain patients with breast cancer who are not responding to treatment, and unlike other drugs in the class, it can be given as a stand-alone treatment to patients who were previously treated with endocrine therapy and chemotherapy,” said Richard Pazdur, MD, Director of the FDA’s Oncology Center of Excellence.

The FDA approved Verzenio for these 2 uses based on clinical trials showing its benefits for patients with HR-positive, HER2-negative advanced or metastatic breast cancer. The most common side effects with Verzenio are diarrhea, neutropenia, nausea, abdominal pain, infections, fatigue, anemia, leukopenia, decreased appetite, vomiting, headache, and thrombocytopenia.

Share this:

Recommended For You
Side-Effects ManagementBreast Cancer
Preparing for Side Effects of Breast Cancer Treatments: A Guide to Common Side Effects and What You Can Do About Them
By Cheryl Bellomo, MSN, RN, OCN, HON-ONN-CG
Oncology Nurse Navigator Cheryl Bellomo provides an overview of possible side effects as well as what can be done to prevent, lessen, or stop them.
SurvivorshipStress ManagementBreast Cancer
Stepping Out from Under the Umbrella of Fear
By Bonnie Annis
Bonnie Annis reflects on her breast cancer diagnosis, dealing with worries of cancer recurrence, using natural remedies, and how fear and stress affect our well-being.
Last modified: March 10, 2022

Subscribe to CONQUER: the patient voice magazine

Receive timely cancer news & updates, patient stories, and more.

Country
Gender
Race or Ethnicity
Profession or Role
Primary Interest