gdc
FDA Approvals, News & UpdatesLymphomaNewsworthy

Calquence Newest Treatment Approved for Mantle-Cell Lymphoma

In October 2017, the FDA accelerated the approval of Calquence for the treatment of adults with mantle-cell lymphoma who have received at least 1 previous therapy.
December 2017 Vol 3 No 6

On October 31, 2017, the FDA accelerated the approval of Calquence (acalabrutinib; from AstraZeneca) for the treatment of adults with mantle-cell lymphoma who have received at least 1 previous therapy. Mantle-cell lymphoma is a rare and fast-growing type of non-Hodgkin lymphoma.

“Mantle cell lymphoma is a particularly aggressive cancer,” said Richard Pazdur, MD, Director of the FDA’s Oncology Center of Excellence. “For patients who have not responded to treatment or have relapsed, Calquence provides a new treatment option that has shown high rates of response for some patients in initial studies.”

This approval was based on a clinical trial of patients with mantle-cell lymphoma that showed that 81% of patients who received Calquence had a complete or partial response to this drug. Serious side effects with Calquence include bleeding, infections, and irregular heartbeat. Women who breastfeed should not take this drug. In addition, new cases of cancer occurred in some patients who used Calquence.

Recommended For You
LymphomaMantle-Cell Lymphoma
Cancer Support Services
Many patients with mantle-cell lymphoma face challenges related to the cost of their medications and other expenses associated with their care. Fortunately, assistance is available for many patients in need.
LymphomaMantle-Cell Lymphoma
Considering a Clinical Trial
Many clinical trials are taking place to investigate new drugs for treating mantle-cell lymphoma. Patients who are thinking about participating in a clinical trial should speak with their healthcare team to get all the facts before making their decision.
LymphomaMantle-Cell Lymphoma
The Hidden Costs of Cancer Treatment
Cancer treatment can be expensive, with numerous unplanned expenses. Fortunately, members of the healthcare team can help guide patients to the resources they need to plan ahead.
LymphomaMantle-Cell Lymphoma
Stem-Cell Transplantation in Mantle-Cell Lymphoma
Although stem-cell transplantation can be an effective treatment for mantle-cell lymphoma, patients have many things to consider when deciding whether this option is appropriate for them.
Last modified: January 16, 2018

Subscribe to CONQUER: the patient voice® magazine

Receive timely cancer news & updates, patient stories, and more.

Country