gdc
FDA Approvals, News & UpdatesLung CancerNewsworthy

FDA Approved Opdivo for Metastatic Small-Cell Lung Cancer

October 2018 Vol 4 No 5

In August 2018, the FDA approved the immunotherapy Opdivo (nivolumab; from Bristol-Myers Squibb) for the treatment of patients with metastatic (spreading) small-cell lung cancer that progressed after platinum-based chemotherapy and at least 1 other therapy.

Opdivo was previously approved by the FDA for patients with non–small-cell lung cancer, the most common type of lung cancer. This new approval makes this immunotherapy also available for patients with small-cell lung cancer, which has fewer treatment options.

This approval was based on results from a clinical trial of 109 patients with or without PD-1 expression who had metastatic small-cell lung cancer that progressed after chemotherapy and at least 1 other therapy.

Overall, in 13 patients with small-cell lung cancer, the cancer responded to treatment with Opdivo, and the responses lasted between 6 months to more than 18 months. This new approval for Opdivo now offers patients with small-cell lung cancer access to immunotherapy, an important addition to the treatment options available for patients with this type of lung cancer.

The side effects with Opdivo in this study were similar to those seen in other studies, and 10% of patients discontinued treatment because of side effects.

Recommended For You
Lung CancerPatient Stories
My CT Scan Routine in Lung Cancer
By Dawn Newton
Dawn Newton, a non-smoker diagnosed with lung cancer, chronicles her emotions as she spends time at the reception area before routine testing and while awaiting the results, knowing that at some point her cancer will stop responding to treatment.
Lung Cancer
Drugs for Lung Cancer
Here are the drugs and financial support services available to patients receiving treatment for Lung Cancer.
Lung Cancer
3 Questions to Ask When Being Diagnosed with Lung Cancer
By Bruce Gershenhorn, DO
Dr. Bruce Gershenhorn explores 3 questions patients should ask after learning they have lung cancer. Knowledge is power.
Last modified: October 27, 2018

Subscribe to CONQUER: the patient voice® magazine

Receive timely cancer news & updates, patient stories, and more.

Country